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Sweat Testing

Welcome to the Sweat Test Working Party Webpage

Working Party Members

Richard MacKay (Chair)
Canterbury Health Laboratories, Christchurch NZ
richard.mackay@cdhb.govt.nz

Ronda Greaves (Secretary)
The Royal Children’s Hospital, Melbourne VIC
ronda.greaves@rch.org.au

Sue Scott
RCPA Chemical Pathology Programs, Adelaide SA
sue.scott@rcpaqap.com.au

James Doery
Monash Medical Centre, Melbourne VIC
james.doery@med.monash.edu.au

Angela Chiriano
The Royal Children’s Hospital, Melbourne VIC
angela.chiriano@rch.org.au

Avantika Mishra
Victorian Clinical Genetics Service, Melbourne VIC
avantika.mishra@ghsv.org.au

John Massie
The Royal Children’s Hospital, Melbourne VIC
(Paediatric Respiratory Medical Group of the Thoracic Society of Australia and New Zealand)
john.massie@rch.org.au

Estrellita Angeles
The Children's Hospital at Westmead, NSW
EstrellA@chw.edu.au

Heather Robins
The Canberra Hospital, ACT
heather.robins@act.gov.au

Michael Metz
Women's and Children's Hospital, Adelaide SA
michael.metz@health.sa.gov.au

Anna Bransden
Pathology Queensland Central, Royal Brisbane & Women's Hospital, QLD
anna_bransden@health.qld.gov.au


REFERENCES AND LINKS

Sweat Testing: Sample Collection and Quantitative Chloride Analysis; Approved Guideline—Third Edition (C34-A3)

This new document is a updated guideline for the performance of the sweat test for the diagnosis of cystic fibrosis. 
New items in this edition:

  • Microvolume procedure for sweat chloride analysis
  • Method validation for sweat chloride
  • Quality assurance for sweat collection
  • Reference ranges for infants and beyond infancy

Preview Sample Pages

 

Sweat testing for cystic fibrosis: standards of performance in Australasia
Coakley J, Scott S, Mackay R, Greaves R, Jolly L, Massie J, Mishra A, Bransden A, Doery JCG, Chiriano A and Robins H
Ann Clin Biochem 2009; 46: 332-337.  DOI:10.1258/acb.2009.009023
http://acb.rsmjournals.com/cgi/reprint/46/4/332


Uncertainty of sweat chloride testing: does the right hand know what the left hand is doing?
Mackay RJ, Florkowski CM, George PM, Sies CW and Woods S.
Ann Clin Biochem 2008; 45: 535-538.  DOI:10.1258/acb.2008.008127
http://acb.rsmjournals.com/cgi/reprint/45/6/535

Total intra-individual variation in sweat sodium and chloride concentrations for the diagnosis of cystic fibrosis.
Koerbin G, Greaves RF, Robins H, Farquhar J and Hickman PE.
Clinica Chimica Acta 2008; 393: 128-129.  DOI:10.1016/j.cca.2008.02.022
http://www.sciencedirect.com/science/journal/00098981

Diagnosis of Cystic Fibrosis by Sweat Testing: Age-Specific Reference Intervals
Mishra A, Greaves R, Smith K, Carlin JB, Wootton A, Stirling R and Massie J.
J Pediatr 2008; 153: 758-763.  DOI:10.1016/j.jpeds.2008.04.067
http://www.jpeds.com/article/S0022-3476(08)00375-2/abstract

Guidelines for Diagnosis of Cystic Fibrosis in Newborns through Older Adults: Cystic Fibrosis Foundation Consensus Report
Farrell PM, Rosenstein BJ, White TB, Accurso FJ, Castellani C, Cutting GR, Durie PR, LeGrys VA, Massie J, Parad RB, Rock MJ and Campbell PW
J Pediatr 2008; 153: S4-S14.  DOI:10.1016/j.jpeds.2008.05.005
http://www.jpeds.com/article/S0022-3476(08)00398-3/abstract

Digital Object Identifier link to search for references by the DOI
http://dx.doi.org

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